Bacterial Vaginosis: Reducing Recurrence with Probiotic Therapy

What is Bacterial Vaginosis?

Bacterial Vaginosis is a disease associated with an imbalance in the normal bacteria in the vagina. What causes this is not yet fully understood. It is marked by a decrease in lactobacilli bacteria and an overgrowth in anaerobic and gram-negative bacteria, known to cause infections. This condition often recurs, especially in sexually active women, even with traditional antibiotics. These women are more likely to develop pelvic inflammatory disease and have a higher risk of contracting the human immunodeficiency virus.

The Benefit of Probiotics and How They May Reduce Recurrence Rates of Bacterial Vaginosis

Probiotics, when taken in the right amounts, can help restore the normal balance of bacteria in the body and improve health by strengthening the immune system.

This research aims to study the possibility of using probiotic treatment as a complementary therapy for nonspecific Vaginosis and reduce its recurrence rate.

The Study Method on Probiotics as a Therapy for Bacterial Vaginosis

173 patients with Bacterial Vaginosis received either a classical antibiotic therapy or a probiotic product. The study group consisted of non-pregnant, sexually active patients who had no other health problems and were not using contraception. 

These patients were divided into three groups. All groups received the classical oral therapy of 500 mg metronidazole twice daily for seven days and topical metronidazole cream for five days. Group A, the control group, did not receive any probiotic treatment. Group B received vaginal probiotic capsules containing a mixture of Lactobacillus Rhamnosus B, Lactobacillus Acidophilus, S. Thermophilus, and Lactobacillus Bulgaricus, taken once daily for six days. Group C received an oral probiotic tablet containing 5 mg Lactobacillus Acidophilus and 3 mg Lactobacillus Bifidus, taken two tablets daily, two hours after ingesting the antibiotic, for ten days.

This therapy was done for three consecutive menstrual periods.

Mucus samples were taken from the cervix and vagina before and after two and three months of treatment to examine the bacterial content.

The Results

Group A had a recurrence rate of more than 50%; Group B had 30%, and Group C had 15%.

The probiotic therapy had its best result in women with Escherichia coli, Proteus and Klebsiella. The oral probiotic helped in lowering the risk of Clostridium infection.

The Conclusion

Probiotics seem to help with bacterial Vaginosis and microflora balance in the intestine and vagina. The most effective way to take probiotics is orally, but vaginal capsules may also be helpful, although more research is needed in this area. We think that taking probiotics along with antibiotics for Bacterial Vaginosis may help decrease the number of recurrences.


Probiotics–A Helpful Additional Therapy for Bacterial Vaginosis

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