How Probiotics help Patients with Colon Cancer after Surgery

What is Colorectal Cancer or Colorectal Carcinoma

Colorectal cancer is a very common type of cancer. It is the third most common cancer and the fourth most common cause of death. 95% of all cases of colon cancer are adenocarcinomas. 

Infection, anastomosis loosening, intra-abdominal abscess, ileus, and bleeding are the most common postoperative surgical complications after colorectal cancer resections. Probiotics reduce the risk of disease in patients undergoing CRC surgery. 

Anastomotic loosening is the most severe complication associated with intestinal surgery. Postoperative ileus (POI) has long been seen as an inevitable consequence of gastrointestinal surgery. 

Ileus that lasts longer than six days serves as a better clinical definition of the extended POI. 

Probiotics may affect the development of intestinal motility. Host surgical manipulations are part of everyday surgical practice in abdominal surgery. The administration of probiotics can result in changes in the metabolite of bacterial fermentation and improved intestinal motility.

The Study on the Use of Probiotics after Colon Cancer Surgery

The study was done on 78 patients with colorectal adenocarcinoma. The patients were divided into two groups. One group took oral probiotics for a year, and the other did not.

The Results

The result of the study showed that there was one fatal outcome in the group of patients who did not take probiotics. There was no significant difference between the number of fatal outcomes in patients who took probiotics and the group of patients who did not take probiotics.

However, all complications were more common in patients who did not take probiotics, but the difference was not statistically significant. The study also showed a substantial difference in the duration of postoperative hospitalization in the group of patients who took probiotics compared to the control group. 

The study showed a statistically significant difference in the occurrence of ileus in the group of patients who did not take probiotics compared to the group of patients who took probiotics. 

However, the study showed that other postoperative complications were not statistically significantly different in the two groups.   

The study showed that the most significant reduction in postoperative complications in the group of patients who took probiotics was in the rectal region and the ascending colon.

Conclusion

Based on the study results, it seems that probiotics can help reduce the number of postoperative complications in patients. Additionally, probiotics may be especially helpful in reducing postoperative complications in patients with tumors in the rectal region, ascending colon, and sigmoid colon

Reference

Usage Of Probiotics And Their Clinical Significance For Surgically Treated Patients Suffering From Colorectal Carcinoma

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