The Effects of B. Lactis on Scaling and Root Planing in Patients with Chronic Periodontitis

What is Scaling and Root Planing?

Scaling and root planing (SRP) is considered the best treatment for periodontitis. However, after SRP treatment, bacteria similar to what was there before treatment can resettle in the site. Because of this, some people think that using accompanying therapies – like antibiotics, antimicrobial photodynamic therapy, and probiotic therapy – can help.

Can Probiotics Help in the treatment of Periodontitis?

Aside from Lactobacillus, studies should also be conducted on other probiotics for possible use in treating periodontitis. One of these is the Bifidobacterium species.

This trial aims to assess the effects of Bifidobacterium animalis subspecies lactis (B. lactis) HN019‐containing probiotic lozenges as an additional treatment to SRP in patients with generalized chronic periodontitis.

What are the Possible Factors in Treating Periodontitis?

In the conduct of this study, the analysts considered other factors, namely: Probing Pocket Depth (PPD), Bleeding on Probing (BoP), Clinical Attachment Level (CAL), Gingival Recession, and Cytokines level. 

PPD of more than 3 millimeters indicates gum disease. BoP is caused by inflammation in the gums. The CAL is used to monitor the progression of periodontitis. A further decrease in CAL means the disease is progressing. Cytokines lead the immune cells to the sites of infection to kill the substances causing it. An increased level implies the existence of inflammation.

The Study Method on Probiotics for Periodontitis

41 chronic periodontitis patients were recruited and monitored before SRP and 30 and 90 days after SRP. They were split into two groups, 20 received SRP and probiotic, and 21 had SRP and placebo. The probiotic group was given lozenges twice a day for 30 days. 

The examiner did clinical measurements on the probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession at six sites per tooth and computed the averages. 

The examiner also noted the presence or absence of bleeding on probing. 

Likewise, the estimated amount of cytokines was determined. 

Plaque samples were taken to get the amount of  B. lactis HN019.

The Results

No patient suffered any adverse effects after the use of probiotics.

The Test group had a decrease in probing pocket depth and a clinical attachment gain significantly higher than the Control group at 90 days. The Test group also had significantly fewer periodontal bacteria, suggesting that probiotics might have helped delay these bacteria’s recolonization of periodontal pockets. Another significant benefit for the Test group is their lower pro-inflammatory cytokine levels, indicating a lessened degree of infection.

Only the Test group showed an increase in B. lactis HN019 on the subgingival biofilm samples at 30 and 90 days, showing the persistence of this probiotic over time.

The Conclusion

B. lactis HN019 can help improve chronic periodontitis when used with SRP based on the additional benefits seen in the study.


Effects of Bifidobacterium Probiotic on the Treatment of Chronic Periodontitis: A Randomized Clinical Trial

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